To stop Valeria Richards, Wolverine, Black Widow, Star-Lord, Hawkeye, and Doctor Doom will work together. She is the most intelligent person on Earth, immortal, and incredibly lonely. She was driven to the verge of insanity after surviving a barrage of nuclear missiles in Southern California and obtaining the reality-altering Cosmic Cube. It's up to our heroes to figure out what odd events are taking place in this radioactive "Dead Zone" and to prevent Valeria from doing a supremely horrible deed.